Ladislaw

Janine S. Ladislaw, Ph.D.

Partner
Registered Patent Attorney
New York

I enjoy helping clients maximize value and safeguard innovations that further their strategic priorities.

Dr. Janine Ladislaw is an Intellectual Property attorney who leverages her technical expertise to counsel clients on high-level global strategic IP issues, including assessing patent portfolios, data and market exclusivity positions, and complex licensing structures in connection with royalty monetization agreements and technology transactions, and devising strategies for patent prosecution.


She has obtained numerous domestic and foreign patents for emerging companies, public corporations, universities and independent research institutions in a wide range of technical areas, including the fields of drug delivery, polymer chemistry, pharmaceuticals and clean technology.

Janine brings nearly two decades of technical knowledge to her intellectual property practice. Prior to joining the firm, she obtained her Ph.D. in Chemistry from the University of Pennsylvania, where her research focused on the development of new metal-catalyzed polymerization methods that yielded polymers with low molecular weight distributions and predictable molecular weights. Additionally, she investigated chiral, non-racemic dendrons and supramolecular dendrimers.

Education

  • Boston College Law School, J.D.
  • University of Pennsylvania, Ph.D. in Organic and Polymer Chemistry
  • College of William and Mary, B.S. in Chemistry, cum laude

Bar and Court Admissions

BAR ADMISSIONS
  • Massachusetts
  • New York (admission pending)
COURT ADMISSIONS
  • U.S. Patent & Trademark Office (Agency)

Experience

ROYALTY MONETIZATION, INTELLECTUAL PROPERTY-RELATED DILIGENCE, AND OPINION ENGAGEMENTS, APPEALS AND DISPUTES
  • Represented California Institute of Technology in appeal proceedings before the USPTO Patent Trial and Appeal Board (PTAB) regarding rejections of claims to methods of synthesizing medicinal products
  • Advised a publicly traded biopharmaceutical company on IP aspects of its acquisition of a clinical-stage biotechnology company focused on treatment of neurological conditions
  • Represented University of Newcastle upon Tyne, a UK public research university, advising on IP aspects of its monetization of a portion of its royalty interests in Rubraca
  • Represented Chiral Technologies, Inc. (a part of Daicel Corporation), the global market leader in enantioselective chromatography, advising on IP aspects of its acquisition of Arbor Biosciences, a pharmaceutical services firm that generates oligonucleotide pools using massively parallel DNA synthesis technology
  • Represented and served as a patent law expert for a pharmaceutical research company in a multi-jurisdiction resolution of various intellectual property and related disputes around the world
  • Represented a pharmaceutical company in seeking FDA regulatory exclusivity
  • Provided a patent invalidity opinion relating to the purification of enantiomerically pure intermediates in pharmaceutical manufacturing
  • Helped investors in life science companies evaluate the patent portfolios and FDA exclusivities that protect the value of their investments
  • Appealed to the USPTO PTAB a rejection of claims to a nasal spray formulation of a corticosteroid for treatment of allergic rhinitis
  • Assisted European counsel on behalf of patent owners in opposition proceedings before the European Patent Office (EPO) and subsequent appeals
PATENTS OBTAINED
  • Applied Polymeric Materials
  • Three-dimensional photoresists via functionalization of polymer thin films fabricated by iCVD (US9163307)
  • Universal solution for growing thin films of electrically conductive nanostructures (US9017773)
  • Nanostructured physically-associating hydrogels for injectable, responsive, and tough biomaterials (US8916683)
  • Hard, impermeable, flexible and conformal organic coatings (US8552131)
  • Methods for producing multiple distinct transistors from a single semiconductor (US7993959)
  • Embolization using degradable crosslinked hydrogels (US7838699)
SYSTEMS AND FORMULATIONS FOR DELIVERY OF PHARMACEUTICALS
  • Drugs and gene carrier particles that rapidly move through mucous barriers (US8957034)
  • Controlled release pharmaceutical delivery device and process for preparation thereof (US7906143)
  • Conjugates comprising a biodegradable polymer and uses therefor (US7785618)
ALTERNATIVE FUELS
  • Glycerol containing fuel mixture for direct injection engines (US8679202)
  • Gene knockout mesophilic and thermophilic organisms, and methods of use thereof, such as for the production of ethanol (US8435770)
DRUGS AND BIOLOGICS
  • Served as the lead chemist on the patent portfolio relating to a small molecule kinase inhibitor that is FDA-approved for the treatment of various leukemias and lymphomas; the drug had a net revenue of more than $1.3 billion in 2021.
  • Compounds and methods for treating mammalian gastrointestinal microbial infections (US8969342)
  • Tricyclic proteasome activity enhancing compounds (US8933087)
  • Aminooxazole inhibitors of cyclin dependent kinases(US8551992)
  • Histone deacetylase inhibitors and methods of use thereof (US8222451)
PRO BONO PATENT PROSECUTION
  • In association with the Volunteer Lawyers for the Arts, represented pro bono an inventor in prosecution of her patent applications to obtain two US patents involving her water purification technology

Publications

  • Lligadas, G.; Ladislaw, J. S.; Guliashvili, T.; Percec, V. Functionally Terminated Poly(methyl acrylate) by SET-LRP Initiated with CHBr3 and CHI3. J. Polym. Sci. Part A: Polym. Chem. 2008, 46, 278-288
  • Percec, V.; Guliashvili, T.; Ladislaw, J. S.; Wistrand, A.; Stjerndahl, A.; Sienkowska, M. J.; Monteiro, M. J.; Sahoo, S. Ultrafast Synthesis of Ultrahigh Molar Mass Polymers by Metal-Catalyzed Living Radical Polymerization of Acrylates, Methacrylates, and Vinyl Chloride Mediated by SET at 25 oC. J. Am. Chem. Soc. 2006, 128, 14156-14165 [Highlighted in Chemical and Engineering News, October 30, 2006, 84(44), 40-41]
  • Mamdouh, W.; Uji-i, H.; Ladislaw, J. S.; Dulcey, A. E.; Percec, V.; De Schryver, F. C.; De Feyter, S. Solvent Controlled Self-Assembly at the Liquid/Solid Interface Revealed by STM. J. Am. Chem. Soc. 2006, 128(1), 317-325
  • Percec, V.; Dulcey, A. E.; Peterca, M.; Ilies, M.; Ladislaw, J.; Rosen, B. M.; Edlund, U.; Heiney, P. A. The Internal Structure of Helical Pores Self-Assembled from Dendritic Dipeptides is Stereochemically Programmed and Allosterically Regulated. Angew. Chem., Int. Ed. 2005, 44, 6516-6521
  • Delozier, D. M.; Orwoll, R. A.; Cahoon, J. F.; Ladislaw, J. S.; Smith, J. G.; Connell, J. W. Polyimide nanocomposites prepared with a novel aromatic surfactant. High Performance Polymers 2003, 15(3), 329-346
  • Delozier, D. M.; Orwoll, R. A.; Cahoon, J. F.; Ladislaw, J. S.; Smith, J. G.; Connell, J. W. Polyimide nanocomposites prepared from high-temperature, reduced charge organo-clays. Polymer 2003, 44(8), 2231-2241

Honors & Involvement

INVOLVEMENT
  • Boston Bar Association (BBA), Advisory Committee Member, Life Sciences Industry Group (2018-2020); Co-Chair of the Life Sciences Committee, Intellectual Property Section (2016-2018)
  • American Chemical Society (ACS), Member
  • American Intellectual Property Law Association (AIPLA), Member
  • Women's Bar Association (WBA) of Massachusetts, Member
  • MassBio MassConnect Company Mentor (2017)

Speaking Engagements

  • “Risk Awareness and Management for Life Science Companies,” MassBio (November 2019)
  • “Teaching Old Drugs New Tricks – Promise and Pitfalls of Drug Repurposing,” New England Healthcare Executive Network (May 2019)
  • “How to Create Value from Inventions,” Harvard Business School New Venture Competition Legal Series (February 2018) 
  • "Top IP Cases in 2017 In-House Counsel Need to Know," Foley Hoag Webinar (December 2017)
  • “Beyond the Bench: Careers in Intellectual Property,” 254th American Chemical Society National Meeting & Exposition, Chemistry and the Law Division (August 2017)
  • Harvard Medical School, Department of Biological Chemistry and Molecular Pharmacology Career Panel 2015 (September 2015)
  • "Corporate and Patent Law Basics for Academic Researchers," F.M. Kirby Neurobiology Center Seminar Series (June 2012)